MCDB 421 — Single-Cell Data Integration
Guest Lecture, University of Michigan, Department of Molecular, Cellular, and Developmental Biology, 2025
Guest lecture on single-cell data integration covering:
- Why single-cell genomics: bulk vs. single-cell resolution
- Single-cell data modalities (scRNA-seq, snATAC-seq, snmC-seq, 10X multiome)
- Challenges with variation and batch effects in sequencing
- Data integration methods (LIGER, Seurat anchors, Harmony)
- Applications to multi-modal single-cell analysis